New Treatment for Severe Asthma May Be on the Horizon

New Treatment for Severe Asthma May Be on the Horizon

A team of researchers at the La Jolla Institute for Immunology has identified a new way to treat severe asthma. The study, published in the Journal of Allergy and Clinical Immunology, found that by blocking a specific interaction between two immune system molecules, it is possible to reduce inflammation and improve lung function in mice with severe asthma.

The interaction that the researchers focused on is between a molecule called HRF and a type of antibody called IgE. HRF is a protein that is produced by cells in the immune system. It helps to signal to other immune cells that there is an allergic reaction happening. IgE is an antibody that binds to allergens, such as pollen or dust mites. When IgE binds to an allergen, it triggers the release of histamine and other inflammatory chemicals.

The researchers found that by blocking the interaction between HRF and IgE, they could reduce inflammation and improve lung function in mice with severe asthma. They are now working to develop a therapy that could be used to treat people with severe asthma.

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This is a promising development for people with severe asthma, which is a chronic condition that affects millions of people worldwide. Current treatments for severe asthma are often not effective, and can have serious side effects. If the researchers are successful in developing a therapy that can block the interaction between HRF and IgE, it could provide a new and effective treatment option for people with severe asthma.

The study was conducted by Toshiaki Kawakami, PhD, and his team at the La Jolla Institute for Immunology. The researchers were supported by grants from the National Institutes of Health.

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About Reeti Garg 353 Articles
Being outstanding in school and college for her academics and sports, little did she know that her passion for writing about unobserved people, stranded things and mysteries of the heart would lead her to become a professional writer later in life! An avid reader and a hardcore movie buff, her favorite past time is listening to music and writing poems. She is a published author and on her way to completing her second book ‘Under the Falling Stars’, a thriller on bisexuality. In this short span of 4 years of being a professional writer, she has been associated with many articles for renowned magazines and newspapers, blogs, short stories and poetries. Names associated with her writing skills are ‘Meri Sajni’, ‘Akinchan Bharat’, ‘Hamara Ghaziabad’, mycity4kids.com. Aspiring to be famous and known as a soulful author one day, she would love to settle someday in the silent disquietedness of London countryside, where she plans to just sip coffee and keep writing trilogies.

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