A noteworthy scientific finding has called into question the widespread assumption about gout. This assumption suggests that lifestyle factors like food and alcohol consumption are the primary causes of the condition. This challenges previously held beliefs about the condition.
According to a study from the University of Otago, genetics plays a major role in developing this problem. By looking at the DNA of millions of people, they found certain genes that increase the risk of gout. This groundbreaking finding challenges accepted knowledge about gout and opens the door to developing stronger treatments and preventatives.
According to a study published in Nature Genetics, inherited genetics explains why some people develop gout while others do not.
According to senior author, Professor Tony Merriman of Otago, the results should help dispel some of the stigma associated with this.
“It is a chronic disease with a genetic basis and is not the fault of the sufferer. The myth that gout is caused by lifestyle or diet needs to be debunked,” he stated.
This common misconception makes sufferers feel ashamed. As a result, some may choose to suffer in silence instead of seeking medical attention for preventive medication that can reduce blood urate levels and ease their discomfort.
People need to understand that specific dietary factors, such as eating red meat, can trigger gout attacks. However, the fundamental causes are high urate levels, crystals in the joints, and an immune system primed to ‘attack’ the crystals. Genetics plays an important role in all of these processes.
The study found numerous immunological genes and immune pathways, offering new targets and strategies for preventing gout attacks.
What is Gout?
According to the Foot Ankle Institute, this type of arthritis impacts the musculoskeletal system—your bones, joints, and muscles.
It occurs due to an accumulation of uric acid in the joints. Uric acid crystallizes in the joints, notably the big toes, when blood levels are too high. The most common gout symptoms include redness, tenderness, swelling, and pain
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